Licensing Opportunity:
Fermentation process for industrial production of plasmid DNA (pDNA).
NTC’s leading DNA fermentation process technology is available for production of DNA vaccines, gene medicines, and plasmids for viral vector production. A standard, non-exclusive technology transfer gives access to the process, know-how and media needed to obtain much higher yields of DNA (up to 2g DNA/liter, or more).
Advantages
The process results in highly purified pDNA, with reduced bacterial (genomic) DNA. This makes the DNA easier to purify from biomass (reduced cell mass per g DNA), dramatically reducing the cost per unit. The DNA is also of higher purity than DNA obtained by comparable methods, and is usually almost 100% covalently closed super-coiled monomer DNA. The process is environmentally friendly because the waste streams are reduced. The results are: best possible product and greater ROI.
Licensing Mechanism
A non-exclusive commercial license is available. Generally, a pilot project (Process Development) determines the optimal fermentation conditions, media, etc. for obtaining the highest possible yield from a given plasmid. Based upon known yield and purity standards for a given plasmid, Technology Transfer (of the patent rights, formulae, know-how, etc.) is completed. Industry standard terms apply.
Licensing Agreement Options
A) Fermentation Process License Agreement: DNA Manufacturing for Resale
B) Fermentation Process Commercial Use License Agreement
