DNAVaccines, H5N1 Proteins, TaqFluorescent Proteins Plasmid DNA Manufacturing DNA Fermentation DNA Process Devlopment Linearized Vectors Genomics

Large Scale Plasmid DNA Processing and Manufacturing
Large Scale Plasmid DNA C of A | Large Scale DNA Pricing | Large Scale DNA Order Form

DNA plasmids and vaccines fermentation
Outsourcing via NTC’s plasmid production service is the ideal answer for all quantities of highly purified DNA (see large scale C of A). Made exclusively with animal product free (APF) HyperGRO media, plasmids are available in Research and GLP (well-characterized) grades, which are perfect for animal efficacy and safety studies, respectively. The NTC process is scalable and tech-transferable to your facility of choice at a later time. Yields (200-2,000mg/L) are superior to other published results, making the HyperGRO plasmid fermentation process the most economical one available. Most importantly, however, is the fact that DNA obtained from this process is of a superior quality, because the cell mass used in purification is less, along with impurities

Quality Assurance
• Optimized fermentation process ensures higher quantity plasmid
• Free of cesium chloride/ethidium bromide and organic solvents
• Endotoxin levels < 0.1EU/mcg
• Wide range of quality control testing
• Transformation and archiving of DNA included
• Formulated to your specifications
• Certificate of Analysis included
• Additional testing available upon request
Advantages • Reliability • Speed • Cost Control • The Results

Advantages

• Highest yield: >200mg/L [batch], 400-2,000mg/L [fed batch]
• Lowest cost
• Greatest purity
• Completely scalable
• Tech transferable to your GMP facility at a later time

Reliability

It makes the most sense to start – and stick with - the most advanced and economical plasmid DNA fermentation and purification process. Not only will this help you to avoid time consuming and costly regulatory burden caused by late stage procedural changes, it also makes the most sense to use the process with the highest initial yield and purity. Why? Because initial yield and purity are directly proportional to the final yield and purity, and the increased yield makes it not only superior but far more cost effective as well. While other manufacturers may use shake flasks or low yield fermentation, NTC’s leading-edge technology results in increased plasmid yield compared to cell mass, dramatically affecting the final purity and cost of the product. While others may charge from $40,000-$150,000 per gram, NTC can save you up to 90% on costs, while providing a superior product. In a world where just 5% cost savings can make a critical difference in profitability, you can’t afford not to use the best technology available.

Applications

Regardless of whether you are using DNA for in vitro studies, DNA vaccination (animal), viral vector production or gene-drug development research, you will find the answer to your supply problems in the only high-yield, cost-effective solution available (the NTC process), which also offers you complete scalability and facility tech-transfer capability at any given point along the way. These advantages not only save you time and money now, but they stand to save you many millions when you get to the GMP manufacturing stage and find that contract facility costs can threaten out-sourcing as a realistic or profitable option. Optimizing the campaign with regard to fermentation alone will reduce facility usage, resulting in significant savings.

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Are you a biotech supplier?

Consider letting NTC out-source your company's entire vector productionschedule.
Your order will receive individual attention from our knowledgeablestaff.
Timely, high quality product is guaranteed with every shipment.


Plasmids, Recombinant Proteins, DNA Vaccines, Viral Vectors, Therapeutic Genes, Fermentation Technology for Gene Therapy and Biotechnology
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