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Nature Technology Corporation’s published patent applications relating to genetic immunization,
DNA vaccines and DNA manufacturing.

1) IMPROVED STRAINS OF E. COLI FOR PLASMID DNA PRODUCTION, Williams, JA, Hodgson, CP (2004) PCT/US2005/28870; WO2006/026125

2) PROCESS FOR PLASMID DNA FERMENTATION, Carnes, AE, Williams, JA (2004) PCT/US2005/29238,
WO2006/023546

3) COMPOSITIONS AND PROCESSES FOR IMPROVED PLASMID DNA PRODUCTION, Williams, JA (2005)
PCT/US2006/03148, WO 2006/081529

4) VECTORS AND METHODS FOR GENETIC IMMUNIZATION, Williams, JA (2005)
PCT/US2006/02174

5) FERMENTATION PROCESS FOR CONTINUOUS PLASMID PRODUCTION, Carnes, AE, (2006)
PCT/US2007/02707.

6) IMPROVED E. COLI PLASMID DNA PRODUCTION, Carnes, AE, Hodgson, CP, Williams, JA (2007)
PCT/US2008/06553

7) PROCESS FOR IMPROVED STRAIN ENGINEERING, Williams, JA, (2007)
PCT/US 008/006548

8) VECTORS AND METHODS FOR GENETIC IMMUNIZATION, Williams, JA (2007)
PCT/US2008/06554

Provisional, Unpublished

9) THERMOSTABLE FUSION PROTEINS AND THERMOSTABLE ADJUVANT, Williams, JA, (2008)
US61/199,651

10)DNA PLASMIDS WITH IMPROVED COPY NUMBER, Williams, JA (2009)
US61/205,561

11) BACTERIAL STRAINS WITH IMPROVED PLASMID STABILITY, Williams, JA (2009)
US61/210,073

Patents

Method of gene transfer using retrotransposons, Hodgson, C.P. (1994): US Patent #5,354,674.

also international filings under Patent Cooperation Treaty, European Patent No. 0506945, issued 7/29/98, Australian Patent No. 699,706.

Mammalian retrotransposons, Hodgson, C.P. (1999): US Patent 5,879,933.


Vectors for Gene Transfer, Hodgson, C.P. (2000): US Patent 6,027,722.


Vectors for Gene Transfer, Hodgson, C.P. (2001): US Patent 6,287,863.


Self-Assembling genes,vectors and uses thereof, Hodgson, C.P., Zink, M.A., and Xu, G.,(2002) US Patent 6,410,220.


Viral packaging signal without gag gene sequences, Hodgson, C.P., Zink, M.A., and Xu, G.,(2003) US Patent 6,573,091.
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