• Enhanced recombinant protein expression in mammalian cells (gene therapy)
• Superior genetic immunization (DNA vaccines)
Description:
An optimized mammalian expression system is now available, combining: the highest levels of RNA/protein expression in mammalian cells; superior E. coli plasmid production yields; optional TPA secretion tag for protein export; simultaneous cloning capability (into both vectors); small vectors for enhanced potency; compliance with regulatory guidance (reduced size, elimination of homology to human genomic DNA).
Features:
• Optimized, chimeric promoter-intron (SV40-CMV-HTLV-1 R-U5-synthetic intron)
• Superior E. coli plasmid production yields (2.5g/L)
• Optional TPA secretion tag
• Smaller vectors for higher potency
• Compliance with regulatory guidance for DNA vaccine vectors
