The advent of DNA vaccines and gene medicines has created a need for a robust plasmid fermentation process with dramatically improved yield and most economical cost of goods. Nature Technology Corporation has created the HyperGRO™ fed-batch fermentation process to address this need, resulting in record yields exceeding 2g/L.

The benefits of the HyperGRO™ fermentation process are well known: the best specific and volumetric yields attainable (1.5-2g/L); highest purity; and greatest economy, results from years of research aimed at maximizing plasmid DNA yield, while maintaining the fidelity and integrity of the plasmid. HyperGRO™ is an optimized, semi-defined media process that allows production facilities to increase their typical plasmid yield dramatically over other methods. Custom batched kits are the way to go with occasional use, while site licensing (commercial, non-comercial) is available for regular users, such as CMOs and GMP production facilities. Finally, for the shake flask user, HyperSHAKE medium is the way to go, typically yielding 10-15 times as much DNA as LB medium. Call today to order easy-to-use HyperSHAKE!